5 11 1 35 catalyst

catalyst 'stabilize' or lower transition state (activated complex)
affects rate, but no change in thermodynamics
inhibitor <-> catalyst
heterogeneous ex. metal solid works as catalyst for a gass
reactants@chemistry -> substrates@biochemistry
'active site' ES complex product P
! dynamics <-> kinetics
Michaelis–Menten K${}_M$をv${}_{max}$とその半分を与える濃度から実験的に求めることができる(wikipedia)
peptide bond cleaved protease

Lec 35 | MIT 5.111 Principles of Chemical Science, Fall 2005